Also indexed as: Differin
Summary of
Interactions with Vitamins, Herbs, and Foods
In some cases, an herb or supplement may appear in more than one category, which may seem
contradictory. For clarification, read the full article for details about the summarized
interactions.
| Depletion or interference |
None known |
| Side effect reduction/prevention |
None known |
| Supportive interaction |
None known |
| Reduced drug absorption/bioavailability |
None known |
| Adverse interaction |
None known |
An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.
Interaction with Foods and Other Compounds
Topical application of adapalene may cause skin irritation in some individuals. This irritation can be worsened when alcohol, astringents, spices, and lime are also applied to the area.1 Sensitive individuals should use caution when using adapalene and other topical compounds.
1. Sifton DW, ed. Physicians Desk Reference. Montvale. NJ: Medical Economics Company, Inc., 2000, 1104–5.